Description

2,4,5-Trifluoropyridine is a high-value fluorinated heterocyclic building block essential for advanced chemical synthesis. This compound is prized for its ability to introduce fluorine atoms and a pyridine scaffold into target molecules, significantly altering their electronic properties, metabolic stability, and bioavailability. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and polymers with unique electronic and surface properties.
• Chemical Research: A versatile building block in medicinal chemistry and discovery chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2,4,5-Trifluoropyridine
CAS No.	837365-04-5
Molecular Formula	C5H2F3N
Molecular Weight	133.07 g/mol
Synonyms	2,4,5-Trifluoropyridine; Pyridine, 2,4,5-trifluoro-; 2,4,5-Trifluoro-pyridine; 837365-04-5; 2,4,5-Trifluoropyridine (CAS 837365-04-5)
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.