Description

D,L-Sulforaphane-D8 is a deuterated isotopologue of the potent natural isothiocyanate sulforaphane, a key bioactive compound derived from cruciferous vegetables. This stable isotope-labeled version is essential for use as an internal standard in quantitative analytical methods, ensuring high accuracy and reliability in research and quality control. It is a critical tool for pharmaceutical development, clinical research, and advanced nutritional studies where precise measurement of sulforaphane and its metabolites is required.

Application

• Quantitative Analytical Internal Standard: Primary use in LC-MS/MS, GC-MS, and HPLC methods for the accurate quantification of sulforaphane in complex biological matrices.
• Pharmacokinetic and Metabolic Studies: Tracing absorption, distribution, metabolism, and excretion (ADME) of sulforaphane in preclinical and clinical research.
• Bioavailability and Nutraceutical Research: Used in studies to measure the precise bioavailability of sulforaphane from dietary sources or supplements.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for drug development and quality assurance of sulforaphane-based formulations.
• Biomarker Assay Development: Critical for developing robust clinical assays to measure sulforaphane-related biomarkers.
• Stable Isotope Dilution Assays (SIDA): Enables highly precise and accurate quantification, minimizing matrix effects and variability.

Basic Information

Product Name	D,L-Sulforaphane-D8
CAS No.	836682-32-7
Molecular Formula	C6H3D8NOS2
Molecular Weight	185.31 g/mol
Synonyms	1-Isothiocyanato-4-(methylsulfinyl)butane-D8; (±)-Sulforaphane-D8; 4-Methylsulfinylbutyl isothiocyanate-D8; SFN-D8; Deuterated Sulforaphane; Rac-Sulforaphane-D8; 4-MSFB-ITC-D8; 1-Isothiocyanato-4-(methylsulfinyl)butane (D8)
EINECS	Contact for details

Quality Control

Our D,L-Sulforaphane-D8 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D8), chemical purity by HPLC, and confirmation of structure. We adhere to relevant standards for high-purity reference materials to guarantee consistency and reliability for your critical research and development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D8)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.