Description

Pf-562771 is a high-purity, small molecule chemical compound with the CAS number 834894-21-2, widely recognized for its role as a potent and selective inhibitor in biochemical research. This compound is critical for advancing studies in cellular signaling pathways, particularly those involving focal adhesion kinase (FAK). It is an essential research-grade material for pharmaceutical R&D, biotechnology, and academic laboratories focused on oncology, cell biology, and drug discovery.

Application

• Biochemical Research: Used as a selective focal adhesion kinase (FAK) inhibitor in enzymatic and cellular assays to study cell adhesion, migration, and proliferation.
• Pharmaceutical R&D: Serves as a key reference standard and pharmacologically active compound in the discovery and development of novel anti-cancer therapeutics.
• Cell Biology Studies: Employed to investigate the role of FAK signaling in tumor progression, metastasis, and angiogenesis.
• Academic Research: A vital tool for universities and research institutes exploring tyrosine kinase signaling networks and their implications in disease.
• High-Throughput Screening (HTS): Utilized as a control compound in screening libraries to identify new drug candidates targeting FAK.

Basic Information

Product Name	Pf-562771
CAS No.	834894-21-2
Molecular Formula	C28H28N6O2
Molecular Weight	480.56 g/mol
Synonyms	PF-562271; PF 562271; VS-6062; Defactinib; N-Methyl-4-[[[4-[[(3S)-3-(methylamino)-3-oxopropyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]methyl]benzamide; FAK Inhibitor PF-562,271; PF562271; Benzamide, N-methyl-4-[[[4-[[(3S)-3-(methylamino)-3-oxopropyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]methyl]-
EINECS	Contact for details

Quality Control

Our Pf-562771 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a desiccator to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.