Description

Elagolix is a nonpeptide, orally active gonadotropin-releasing hormone (GnRH) antagonist. It is a highly specific active pharmaceutical ingredient (API) designed to suppress the production of sex hormones, offering a targeted therapeutic approach. This compound is primarily utilized in the pharmaceutical industry for the development and manufacture of treatments for hormone-dependent conditions. Its precise mechanism makes it a critical component for advanced therapeutic applications.

Application

• Primary Active Pharmaceutical Ingredient (API) in prescription medications for the management of endometriosis-associated pain.
• Key component in therapeutic formulations for the management of uterine fibroids (leiomyomas).
• Used in clinical research and development of novel hormone suppression therapies.
• Essential for the synthesis of finished dosage forms, such as tablets and capsules, in GMP-compliant facilities.
• Reference standard for analytical method development and quality control testing in pharmaceutical laboratories.

Basic Information

Product Name	Elagolix
CAS No.	834153-87-6
Molecular Formula	C32H30F5N3O5
Molecular Weight	631.59 g/mol
Synonyms	Elagolix; NBI-56418; 4-[[(1R)-2-[5-(2-Fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)benzoyl]amino]-2-pyridinyl]-1-phenylethyl]amino]-4-oxobutanoic Acid; (R)-2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzamido)pyridin-2-yl)-N-(4-methoxy-4-oxobutanoyl)-1-phenylethanaminium; ABT-620; GnRH Antagonist ABT-620
EINECS	Contact for details

Quality Control

Our Elagolix is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.