Description

1-(2-Fluoro-6-(Trifluoromethyl)Benzyl)-6-Methylpyrimidine-2,4(1H,3H)-Dione is a specialized fluorinated pyrimidine derivative, a high-value building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethyl groups, is engineered to impart unique electronic and steric properties critical for developing novel active compounds. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create new molecules with enhanced metabolic stability, bioavailability, and target specificity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Chemical Biology Probe: Employed as a scaffold for creating tool compounds and probes to study enzyme mechanisms and biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials requiring fluorinated aromatic components for specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(2-Fluoro-6-(Trifluoromethyl)Benzyl)-6-Methylpyrimidine-2,4(1H,3H)-Dione
CAS No.	830346-47-9
Molecular Formula	C13H10F4N2O2
Molecular Weight	302.23 g/mol
Synonyms	6-Methyl-1-[(2-fluoro-6-(trifluoromethyl)phenyl)methyl]pyrimidine-2,4(1H,3H)-dione; 1-[(2-Fluoro-6-(trifluoromethyl)phenyl)methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione; 6-Methyl-1-((2-fluoro-6-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione; Fluorinated Pyrimidine Derivative; TFMP-Benzyl Pyrimidinedione
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluoro-6-(Trifluoromethyl)Benzyl)-6-Methylpyrimidine-2,4(1H,3H)-Dione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.