Description

(R)-(+)-Etomoxir Sodium Salt is a high-purity, enantiomerically pure sodium salt of the carnitine palmitoyltransferase-1 (CPT-1) inhibitor etomoxir. This compound matters as a critical research-grade biochemical tool for studying fatty acid oxidation and metabolic pathways in cellular and animal models. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic disorders, oncology, and cardiovascular disease.

Application

• Metabolic Research: A key tool for inhibiting mitochondrial fatty acid β-oxidation by blocking CPT-1, used to study energy metabolism, insulin resistance, and the metabolic switch in various cell types.
• Cardiovascular Disease Studies: Employed in preclinical research to investigate the role of fatty acid metabolism in heart failure, myocardial ischemia, and cardiac hypertrophy.
• Oncology Research: Used to explore the dependency of certain cancer cells on fatty acid oxidation for growth and survival, supporting drug discovery in cancer metabolism.
• Pharmacology & Toxicology: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the development and analysis of metabolic modulators.
• Biochemical Assay Development: Utilized as a specific inhibitor in enzyme activity assays and high-throughput screening platforms targeting metabolic enzymes.

Basic Information

Product Name	(R)-(+)-Etomoxir Sodium Salt
CAS No.	828934-41-4
Molecular Formula	C15H20NaO4
Molecular Weight	287.31 g/mol
Synonyms	(R)-Etomoxir Sodium Salt; (+)-Etomoxir Sodium Salt; (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]oxirane-2-carboxylic Acid Sodium Salt; Sodium (R)-(+)-Etomoxir; (R)-Etomoxir Na Salt; (R)-Etomoxir Sodium; (R)-Etomoxir Sodium Salt Hydrate (if applicable); CPT-1 Inhibitor (R)-enantiomer Sodium Salt
EINECS	Contact for details

Quality Control

Our (R)-(+)-Etomoxir Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet rigorous research standards. A Certificate of Analysis (COA) detailing specific results for assay, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.