Description

2-Fluoro-4-(Methylsulfonyl)Toluene is a high-value fluorinated aromatic sulfone building block, essential for advanced chemical synthesis. Its unique structure, featuring both fluorine and a methylsulfonyl group on a toluene backbone, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly in kinase inhibitor and anti-inflammatory agent development.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for functionalized polymers and liquid crystals, contributing to advanced material properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the 2-fluoro-4-(methylsulfonyl)phenyl moiety into complex molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.

Basic Information

Product Name	2-Fluoro-4-(Methylsulfonyl)Toluene
CAS No.	828270-60-6
Molecular Formula	C8H9FO2S
Molecular Weight	188.22 g/mol
Synonyms	1-Fluoro-2-methyl-5-(methylsulfonyl)benzene; 2-Methyl-5-(methylsulfonyl)fluorobenzene; 4-(Methylsulfonyl)-2-fluorotoluene; 2-Fluoro-4-methylsulfonyltoluene; Toluene, 2-fluoro-4-(methylsulfonyl)-; 2-Fluoro-4-(methanesulfonyl)toluene; 5-Fluoro-2-methylphenyl methyl sulfone
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Methylsulfonyl)Toluene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC/GC is provided with each shipment to guarantee supply reliability and product integrity for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.