Description

2-Fluoro-5-(Methylsulfonyl)Toluene is a high-value fluorinated aromatic sulfone building block, essential for advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a methylsulfonyl group on a toluene backbone, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine and sulfone groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis, leveraging the electron-withdrawing sulfone group.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-(Methylsulfonyl)Toluene
CAS No.	828270-58-2
Molecular Formula	C8H9FO2S
Molecular Weight	188.22 g/mol
Synonyms	1-Fluoro-2-methyl-4-(methylsulfonyl)benzene; 2-Methyl-5-(methylsulfonyl)fluorobenzene; 5-(Methylsulfonyl)-2-fluorotoluene; Toluene, 2-fluoro-5-(methylsulfonyl)-; 2-Fluoro-5-methanesulfonyltoluene; 2-Fluoro-α,α-dimethylbenzenemethanesulfonic acid (related); 828270-58-2
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Methylsulfonyl)Toluene is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.