Description

3-Trifluoromethoxy-Pyridin-4-Ylamine is a high-purity, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoromethoxy-substituted pyridine core, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Trifluoromethoxy-Pyridin-4-Ylamine
CAS No.	827586-90-3
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	4-Amino-3-(trifluoromethoxy)pyridine; 3-(Trifluoromethoxy)pyridin-4-amine; 4-Pyridinamine, 3-(trifluoromethoxy)-; 3-Trifluoromethoxy-4-aminopyridine; 4-Amino-3-trifluoromethoxypyridine; 3-Trifluoromethoxypyridin-4-ylamine
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethoxy-Pyridin-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.