Description

1H-Indole-1-Sulfonyl Chloride, 2,3-Dihydro- is a specialized sulfonyl chloride derivative of indoline, serving as a versatile and reactive synthetic building block. Its core value lies in enabling the efficient introduction of the sulfonyl moiety into target molecules, a critical step in medicinal chemistry and materials science. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that incorporate sulfonyl functional groups.
• Organic Synthesis Reagent: Acts as a sulfonylation agent in various organic transformations to create sulfonamides, sulfonate esters, and other sulfonyl-containing compounds.
• Material Science Research: Employed in the development of specialty polymers, dyes, and functional materials where the indoline-sulfonyl scaffold imparts specific properties.
• Chemical Biology Probes: Useful for modifying proteins or other biomolecules to study biological pathways or create diagnostic tools.

Basic Information

Product Name	1H-Indole-1-Sulfonyl Chloride, 2,3-Dihydro-
CAS No.	816449-15-7
Molecular Formula	C8H8ClNO2S
Molecular Weight	217.67 g/mol
Synonyms	2,3-Dihydro-1H-indole-1-sulfonyl chloride; Indoline-1-sulfonyl chloride; 1-Sulfonylchloride-2,3-dihydroindole; 1H-Indole-1-sulfonyl chloride, 2,3-dihydro-; 816449-15-7; 2,3-Dihydroindole-1-sulfonyl chloride; 1-(Chlorosulfonyl)indoline
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Sulfonyl Chloride, 2,3-Dihydro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.