Description

Pkcε Inhibitor Scramble Peptide CAS NO 813416-34-1 is a synthetic, cell-permeable peptide designed to selectively inhibit the epsilon isoform of protein kinase C (PKCε). This compound serves as a critical negative control in research, specifically to validate the biological effects of active PKCε inhibitory peptides by scrambling the amino acid sequence. It is an essential tool for researchers in academic, pharmaceutical, and biotechnology laboratories investigating signal transduction pathways, cardiac function, neurological disorders, and cancer biology.

Application

• Biomedical Research Control: Serves as a critical negative control in experiments utilizing active PKCε inhibitory peptides to confirm target specificity and rule out off-target effects.
• Signal Transduction Studies: Used to investigate the role of PKCε in complex cellular signaling cascades related to growth, differentiation, and apoptosis.
• Cardiovascular Research: Applied in studies of ischemic preconditioning, cardiac hypertrophy, and heart failure where PKCε is a key regulatory enzyme.
• Neuroscience & Pain Research: Utilized to explore PKCε's involvement in neurotransmitter release, synaptic plasticity, chronic pain mechanisms, and neurodegenerative diseases.
• Oncology Research: Employed in cancer studies to dissect the pro-survival and metastatic roles of PKCε in various tumor cell lines.
• Drug Discovery & Validation: Acts as a essential reference compound in high-throughput screening and the preclinical validation of novel PKCε-targeted therapeutics.

Basic Information

Product Name	Pkcε Inhibitor Scramble Peptide
CAS No.	813416-34-1
Molecular Formula	C41H72N14O9
Molecular Weight	881.1 g/mol
Synonyms	PKC Epsilon Inhibitor Scramble Peptide; PKCε Inhibitor Scrambled Control; εV1-2 Scramble Peptide; Scrambled PKCε Inhibitor; PKCε Negative Control Peptide; H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH; EAVSLKPT; Scrambled version of εV1-2
EINECS	Contact for details

Quality Control

Every batch of our Pkcε Inhibitor Scramble Peptide is synthesized and purified under stringent conditions to ensure the highest standard of research-grade quality. Identity and purity are verified by multiple orthogonal analytical methods, including Mass Spectrometry (MS) and High-Performance Liquid Chromatography (HPLC). A comprehensive Certificate of Analysis (COA) detailing purity, amino acid analysis, and solvent content is provided with each shipment to guarantee reproducibility and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Amino Acid Composition	Passes analysis
Net Peptide Content	≥ 80%
Solvent Content (TFA)	≤ 5%
Water Content (KF)	≤ 3%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.