Description

5-Bromo-2-Methoxy-4-Methylbenzene-1-Sulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative essential for advanced organic synthesis. This compound serves as a critical building block for introducing the sulfonamide moiety, enabling the creation of complex molecules with tailored properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides that require the sulfonamide functional group for bioactivity.
• Material Science Research: Building block for creating specialized polymers, dyes, and photoactive materials where the sulfonyl chloride group facilitates further functionalization.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries for client R&D programs.

Basic Information

Product Name	5-Bromo-2-Methoxy-4-Methylbenzene-1-Sulfonyl Chloride
CAS No.	808134-00-1
Molecular Formula	C8H8BrClO3S
Molecular Weight	299.57 g/mol
Synonyms	4-Bromo-5-Methoxy-2-Methylbenzenesulfonyl Chloride; 2-Methoxy-5-bromo-4-methylbenzenesulfonyl chloride; 1-Bromo-4-methoxy-5-methyl-2-sulfonylchloridobenzene; 5-Bromo-2-methoxy-p-toluenesulfonyl chloride; 808134-00-1; Benzenesulfonyl chloride, 5-bromo-2-methoxy-4-methyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxy-4-Methylbenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.