Description

5-Fluoro-2-Hydroxymethyl Pyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a reactive hydroxymethyl group and a fluorine substituent on the pyridine ring, enabling precise molecular modifications for creating high-value target molecules. Pharmaceutical, agrochemical, and material science research and development teams need it for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers and liquid crystals, where the pyridine core contributes to self-assembly and electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	5-Fluoro-2-Hydroxymethyl Pyridine
CAS No.	802325-29-7
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	2-(Hydroxymethyl)-5-fluoropyridine; 5-Fluoro-2-pyridinemethanol; (5-Fluoropyridin-2-yl)methanol; 5-Fluoro-2-(hydroxymethyl)pyridine; 5-Fluoro-2-pyridylmethanol; 802325-29-7; 5-Fluoro-2-hydroxymethylpyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Hydroxymethyl Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.