Description

2-Amino-4,6-Bis(Trifluoromethyl)Nicotinamide is a high-value, fluorinated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its molecular structure, featuring multiple trifluoromethyl groups, imparts unique electronic and steric properties essential for developing compounds with enhanced stability and bioactivity. This specialized intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by fine chemical manufacturers producing advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and environmental stability.
• Ligand and Catalyst Development: Serves as a sophisticated ligand scaffold in organometallic chemistry and catalysis for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds and molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Amino-4,6-Bis(Trifluoromethyl)Nicotinamide
CAS No.	89990-38-5
Molecular Formula	C9H5F6N3O
Molecular Weight	285.15 g/mol
Synonyms	2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide; 3-Carbamoyl-2-amino-4,6-bis(trifluoromethyl)pyridine; 4,6-Bis(trifluoromethyl)-2-aminonicotinamide; Nicotinamide, 2-amino-4,6-bis(trifluoromethyl)-; 2-Amino-4,6-di(trifluoromethyl)nicotinamide
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4,6-Bis(Trifluoromethyl)Nicotinamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Our standard quality commitment includes rigorous purity analysis by HPLC, identity confirmation via FT-IR and NMR spectroscopy, and control of specified impurities. A detailed Certificate of Analysis (COA) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container must be kept tightly sealed due to the compound's sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.