Description

(Chlorosulfonyl)Carbamic Acid Benzyl Ester is a specialized organic synthesis intermediate featuring both a reactive chlorosulfonyl group and a carbamate-protected amine. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing sulfonamide and sulfamate derivatives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide or sulfamate functional groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the chlorosulfonyl moiety is incorporated into the final active compound.
• Peptide Modification: Serves as a reagent for the selective modification of amino acids or peptides to introduce sulfonyl-based protecting groups or labels.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent in the production of specialty polymers with specific functional properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Material Science Research: Acts as a building block for creating novel organic frameworks or surface-functionalized materials.

Basic Information

Product Name	(Chlorosulfonyl)Carbamic Acid Benzyl Ester
CAS No.	89979-13-5
Molecular Formula	C8H8ClNO4S
Molecular Weight	249.67 g/mol
Synonyms	Benzyl N-(chlorosulfonyl)carbamate; Carbamic acid, N-(chlorosulfonyl)-, benzyl ester; Benzyl chlorosulfonylcarbamate; N-(Chlorosulfonyl)carbamic Acid Benzyl Ester; Benzyl (chlorosulfonyl)carbamate; (Chlorosulfonyl)carbamic acid phenylmethyl ester; Benzyloxycarbonylsulfamoyl chloride (related); Z-Sulfamoyl Chloride (common abbreviation)
EINECS	Contact for details

Quality Control

Our (Chlorosulfonyl)Carbamic Acid Benzyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC or titration), identification (by IR and NMR), and impurity profiles. Our quality systems support development from research to commercial scale, ensuring reliable supply for critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (by GC)	Contact for details
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.