Description

11-Oxo-Prosta-5Z,9,12E,14Z-Tetraen-1-Oic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is critical for studying inflammatory pathways, receptor binding, and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on metabolic and inflammatory disease research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of eicosanoid signaling, cyclooxygenase pathways, and inflammation mechanisms.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs targeting prostaglandin receptors (EP, FP, DP receptors).
• Analytical Standard: Employed in HPLC, LC-MS, and GC-MS methods for quantitative analysis and method validation in complex matrices.
• Academic Research: Facilitates fundamental research in physiology, pharmacology, and cell biology related to lipid mediators.

Basic Information

Product Name	11-Oxo-Prosta-5Z,9,12E,14Z-Tetraen-1-Oic Acid
CAS No.	89886-60-2
Molecular Formula	C₂₀H₂₈O₃
Molecular Weight	316.44 g/mol
Synonyms	11-Oxo-PG; 11-Oxoprosta-5Z,9,12E,14Z-tetraenoic acid; 11-Keto-Prosta-5Z,9,12E,14Z-tetraenoic Acid; 11-Oxo-prostaglandin; 11-Oxo-PG analog; Prostaglandin 11-keto derivative; 11-Keto-PG; 11-Oxo-PG intermediate
EINECS	Contact for details

Quality Control

Every batch of 11-Oxo-Prosta-5Z,9,12E,14Z-Tetraen-1-Oic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specification results. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.