Description

9Beta,11Alpha,15S-Trihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, Tris (Hydroxymethyl)Aminomethane Salt is a high-purity, chemically defined salt form of a key prostaglandin derivative, offering enhanced stability and solubility for advanced research and development. This compound is critical for its role as a precise biochemical tool in studying inflammatory and physiological pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on prostaglandin-based therapeutics and analytical standards.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quality control and assay development of prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a critical reagent in in vitro and in vivo studies to investigate prostaglandin receptor activity, signal transduction, and related metabolic processes.
• Drug Discovery & Development: Acts as a key intermediate or a biological probe in the synthesis and screening of novel anti-inflammatory and cardiovascular drug candidates.
• Analytical Chemistry: Employed in method development and validation for chromatographic (HPLC, LC-MS) analyses of complex biological matrices.
• Cell Culture & Pharmacology: Applied in cell-based assays to study cellular responses, cytokine release, and other prostaglandin-mediated effects.

Basic Information

Product Name	9Beta,11Alpha,15S-Trihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, Tris (Hydroxymethyl)Aminomethane Salt
CAS No.	89847-02-9
Molecular Formula	C23H38O8 • C4H11NO3
Molecular Weight	Contact for details
Synonyms	Prostaglandin H2 Tromethamine Salt; PGH2-Tris Salt; 9β,11α,15S-Trihydroxyprosta-5Z,13E-dien-1-oic Acid Trometamol Salt; (5Z,13E)-(9β,11α,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid Compound with 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tromethamine Salt of Prostaglandin H2; PGH2 Trometamol; TRIS Salt of Prostaglandin H2
EINECS	Contact for details

Quality Control

Our 9Beta,11Alpha,15S-Trihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, Tris (Hydroxymethyl)Aminomethane Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We adhere to cGMP guidelines for the production of reference standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.