Description

5A-Androstan-3B-Ol-17-One (Epiandrosterone) (2,2,4,4-D4, 98%) is a high-purity, deuterium-labeled analog of the endogenous steroid hormone epiandrosterone. This compound is critical for research and development applications requiring precise metabolic and pharmacokinetic studies, where its isotopic label provides a distinct analytical signature. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on endocrinology, steroid biochemistry, and the development of analytical reference standards.

Application

• Internal Standard for LC-MS/MS: Serves as a stable isotope-labeled internal standard for the quantitative bioanalysis of epiandrosterone and related steroid metabolites in biological matrices.
• Metabolic Pathway Tracing: Used in deuterium tracing studies to investigate steroidogenesis, metabolic fluxes, and enzyme activity in vitro and in vivo.
• Pharmaceutical Reference Material: Acts as a certified reference material (CRM) for method development, validation, and quality control in drug discovery and clinical research.
• Endocrinology Research: A key tool for studying androgen metabolism, hormone regulation, and disorders related to steroid hormone imbalance.
• Doping Control Analysis: Employed in sports anti-doping laboratories as a reference compound for the accurate detection of endogenous steroid abuse.

Basic Information

Product Name	5A-Androstan-3B-Ol-17-One (Epiandrosterone) (2,2,4,4-D4, 98%)
CAS No.	89685-09-6
Molecular Formula	C19H26D4O2
Molecular Weight	290.46 g/mol (for deuterated form)
Synonyms	Epiandrosterone-d4; 3β-Hydroxy-5α-androstan-17-one-d4; 5α-Androstan-3β-ol-17-one-2,2,4,4-d4; Isoandrosterone-d4; 17-Oxo-5α-androstan-3β-ol-d4; Androstanolone-d4 (related); 3β-Hydroxy-5α-androstan-17-one-2,2,4,4-d4
EINECS	Contact for details

Quality Control

This high-grade deuterated standard is manufactured under strict quality control protocols to ensure isotopic enrichment and chemical purity. Every batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing the assay, isotopic purity (D4, 98%), and identification data, supporting compliance with GMP/GLP guidelines for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D4)	≥ 98% (by MS)
Chemical Purity	≥ 98%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.