Description

2,3,5-Tribromobenzotrifluoride is a halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular structure, which combines bromine substituents with a trifluoromethyl group to impart specific reactivity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly as an intermediate in cross-coupling reactions and for introducing fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated, fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the bromine atoms offer sites for further functionalization.
• Material Science Precursor: Serves as a monomer or intermediate in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Reagent: Utilized in nucleophilic aromatic substitution and as a starting material for generating more complex trifluoromethylated compounds.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and exploring new synthetic pathways involving polyhalogenated arenes.

Basic Information

Product Name	2,3,5-Tribromobenzotrifluoride
CAS No.	89642-34-2
Molecular Formula	C7H2Br3F3
Molecular Weight	386.80 g/mol
Synonyms	1,2,4-Tribromo-5-(trifluoromethyl)benzene; Benzene, 1,2,4-tribromo-5-(trifluoromethyl)-; 2,3,5-Tribromo-α,α,α-trifluorotoluene; Tribromobenzotrifluoride; 2,3,5-Tribromo(trifluoromethyl)benzene; α,α,α-Trifluoro-2,3,5-tribromotoluene
EINECS	Contact for details

Quality Control

Our 2,3,5-Tribromobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.