Description

5-Chloro-2-Fluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on a trifluoromethylated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzotrifluoride scaffold.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Intermediate in the production of specialty polymers and small molecules for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new reactions and creating compound libraries via cross-coupling and nucleophilic substitution reactions.
• Dye and Pigment Industry: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	5-Chloro-2-Fluorobenzotrifluoride
CAS No.	89634-74-2
Molecular Formula	C7H3ClF4
Molecular Weight	198.55 g/mol
Synonyms	1-Chloro-4-fluoro-2-(trifluoromethyl)benzene; 2-Chloro-5-fluorobenzotrifluoride; 5-Chloro-2-fluorobenzylidene trifluoride; 2-Fluoro-5-chlorobenzotrifluoride; 4-Fluoro-1-chloro-2-(trifluoromethyl)benzene; α,α,α-Trifluoro-5-chloro-2-fluorotoluene; 5-Chloro-2-fluoro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluorobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.48 g/cm³
Boiling Point	~165-170°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.