Description

1-Methyl-1H-Pyrazole-3-Sulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules with high efficiency. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the sulfonyl moiety imparts specific biological activity.
• Functional Material Precursor: Employed in the research and development of specialty polymers, dyes, and liquid crystals that require sulfonamide linkages.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in probe development and bioconjugation strategies.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Methyl-1H-Pyrazole-3-Sulfonyl Chloride
CAS No.	89501-90-6
Molecular Formula	C4H5ClN2O2S
Molecular Weight	180.61 g/mol
Synonyms	1-Methyl-1H-pyrazole-3-sulfonyl chloride; 3-Pyrazolesulfonyl chloride, 1-methyl-; 1-Methylpyrazole-3-sulfonyl chloride; 1-Methyl-3-pyrazolesulfonyl chloride; 1-Methyl-1H-3-pyrazolesulfonyl chloride; N-Methylpyrazole-3-sulfonyl chloride; 89501-90-6
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Pyrazole-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.