Description

5-Chloro-2-Hydroxyphenylboronic Acid is a versatile organoboron compound that serves as a key building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a phenolic hydroxyl group for further derivatization. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in constructing biaryl structures common in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated phenolic architectures.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and organic electronic materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new catalytic processes and constructing complex molecular libraries.
• Ligand Synthesis: The hydroxyl and boronic acid groups allow it to be transformed into sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Diagnostic Reagents: Potential use in the development of sensors and biochemical assay components due to its specific binding properties.

Basic Information

Item	Details
Product Name	5-Chloro-2-Hydroxyphenylboronic Acid
CAS No.	89488-25-5
Molecular Formula	C6H6BClO3
Molecular Weight	172.37 g/mol
Synonyms	5-Chloro-2-hydroxybenzeneboronic acid; (5-Chloro-2-hydroxyphenyl)boronic acid; 2-Hydroxy-5-chlorophenylboronic acid; 5-Chlorosalicylboronic Acid; Boronic acid, B-(5-chloro-2-hydroxyphenyl)-; CAS 89488-25-5
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Hydroxyphenylboronic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant assays. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.