Description

4-Bromo-2-Nitrobenzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients and specialty chemicals. This intermediate is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with sulfonamide backbones.
• Dye and Pigment Manufacturing: Acts as a reactive intermediate for creating sulfonated azo dyes and specialty colorants.
• Polymer Chemistry: Employed in the modification of polymers and the synthesis of monomers for high-performance materials.
• Chemical Biology Research: Useful as a labeling or cross-linking reagent for probing protein structure and function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Bromo-2-Nitrobenzene-1-Sulfonyl Chloride
CAS No.	89465-98-5
Molecular Formula	C6H3BrClNO4S
Molecular Weight	300.51 g/mol
Synonyms	1-Bromo-4-(chlorosulfonyl)-2-nitrobenzene; 2-Nitro-4-bromobenzenesulfonyl chloride; 4-Bromo-2-nitrobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-2-nitro-; p-Bromo-o-nitrobenzenesulfonyl chloride; 4-Bromo-2-nitro-1-sulfonyl chloride benzene; BNBS-Cl
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Nitrobenzene-1-Sulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.