Description

5-Bromo-2,3-Difluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it an invaluable intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used to construct complex molecules for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluoropyridine core.
• Material Science: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi) to create complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for studying the effects of fluorine substitution on molecular properties like metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Used to synthesize novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	5-Bromo-2,3-Difluoropyridine
CAS No.	89402-44-8
Molecular Formula	C5H2BrF2N
Molecular Weight	193.98 g/mol
Synonyms	2,3-Difluoro-5-bromopyridine; 5-Bromo-2,3-difluoropyridine; 2,3-Difluoro-5-bromo-pyridine; Pyridine, 5-bromo-2,3-difluoro-; 89402-44-8; 5-Br-2,3-F2Py
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Difluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.