Description

3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine motifs contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic materials and liquid crystals for electronic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	89402-28-8
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-5-trifluoromethylpicolinic acid; 5-(Trifluoromethyl)-3-fluoropyridine-2-carboxylic acid; 3-Fluoro-5-(trifluoromethyl)-2-pyridinecarboxylic acid; 3-Fluoro-5-(trifluoromethyl)picolinic acid; 89402-28-8; FC-1133 (Potential research code)
EINECS	Contact for details

Quality Control

We supply 3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.