Description

5-Methyl-3-thiophenesulfonyl chloride is a specialized organosulfur building block and sulfonylating agent. This compound is critical for introducing the 5-methyl-3-thiophenesulfonyl moiety into target molecules, enabling the synthesis of novel materials and bioactive compounds. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex sulfonamide derivatives and functionalized heterocycles.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Building block for creating functionalized polymers, conductive materials, and organic electronic components based on thiophene scaffolds.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeling reagents for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and the production of high-value specialty chemicals.

Basic Information

Product Name	5-Methyl-3-thiophenesulfonyl Chloride
CAS No.	89379-25-9
Molecular Formula	C5H5ClO2S2
Molecular Weight	196.68 g/mol
Synonyms	3-Thiophenesulfonyl chloride, 5-methyl-; 5-Methylthiophene-3-sulfonyl chloride; 5-Methyl-3-thienylsulfonyl chloride; 89379-25-9; 5-Methyl-thiophene-3-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-3-thiophenesulfonyl chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and IR spectroscopy for identity confirmation. Certificates of Analysis (COA) documenting all relevant specifications are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.