Description

(-)-2-[(Propionyl-L-Aile-L-Leu-L-Leu-)Amino]-5-Guanidinovaleraldehyde is a specialized, high-purity synthetic peptide derivative designed for advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate or reference standard in the study of enzyme inhibition and proteolytic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing novel therapeutic agents targeting specific proteases. Its precise stereochemistry and functional groups make it an invaluable tool for mechanistic studies and high-throughput screening assays.

Application

• Protease Inhibitor Research: Acts as a key intermediate or model substrate in the study of serine and cysteine proteases.
• Pharmaceutical Development: Serves as a building block or reference standard in the synthesis and optimization of novel therapeutic candidates.
• Biochemical Assays: Used in enzymatic activity assays and high-throughput screening (HTS) platforms to identify and characterize new inhibitors.
• Academic Research: Employed in universities and research institutes for fundamental studies on enzyme kinetics and mechanism of action.
• Peptide Chemistry: Utilized as a specialized reagent in peptide synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(-)-2-[(Propionyl-L-Aile-L-Leu-L-Leu-)Amino]-5-Guanidinovaleraldehyde
CAS No.	89342-57-4
Molecular Formula	C28H53N7O5
Molecular Weight	567.77 g/mol
Synonyms	Propionyl-L-Ala-L-Leu-L-Leu-Arg-H; Leupeptin Hemisulfate Precursor; Acetyl-Leu-Leu-Arg-al; (-)-2-[(Propionyl-L-Ala-L-Leu-L-Leu-)Amino]-5-Guanidinovaleraldehyde; Protease Inhibitor Peptide Aldehyde; L-Ala-L-Leu-L-Leu-Arg-H, Propionyl-; 89342-57-4; Ala-Leu-Leu-Arg-al
EINECS	Contact for details

Quality Control

Every batch of (-)-2-[(Propionyl-L-Aile-L-Leu-L-Leu-)Amino]-5-Guanidinovaleraldehyde is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.