Description

Cilostazol-D11 CAS NO 89332-50-3 is a deuterated analog of the antiplatelet and vasodilator drug Cilostazol, where eleven hydrogen atoms are replaced with the stable isotope deuterium. This high-purity labeled compound is essential for use as an internal standard in quantitative bioanalytical methods, ensuring unparalleled accuracy and reliability in pharmacokinetic and metabolic studies. It is a critical material for pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers engaged in the development and quality control of Cilostazol-based therapies.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the precise quantification of Cilostazol in biological matrices (plasma, serum, tissue).
• Facilitates drug metabolism and pharmacokinetics (DMPK) studies, enabling accurate tracking of the parent drug's absorption, distribution, metabolism, and excretion (ADME) profile.
• Critical component in clinical trial bioanalysis to support regulatory submissions (e.g., to FDA, EMA) for new drug applications or generic versions of Cilostazol.
• Used in pharmaceutical quality control laboratories for method development and validation to ensure batch consistency and purity.
• Enables metabolite identification and profiling studies due to its isotopic signature, which helps distinguish drug-derived compounds from endogenous substances.
• Supports forensic and anti-doping analysis where precise measurement of Cilostazol levels is required.

Basic Information

Product Name	Cilostazol-D11
CAS No.	89332-50-3
Molecular Formula	C20H16D11N5O2
Molecular Weight	378.50 g/mol (approximate)
Synonyms	6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone-D11; OPC-13013-D11; Pletal-D11; 3,4-Dihydro-6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-2(1H)-quinolinone-D11; Cilostazol (D11); Cilostazol-d11; Deuterated Cilostazol; Cilostazol Internal Standard
EINECS	Contact for details

Quality Control

Our Cilostazol-D11 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D11, D10, D9 content), chemical purity by HPLC, and confirmation of structure. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable and reproducible performance in your assays. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or Certificate of Analysis. This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity (D11)	≥98.0 atom % D
Chemical Purity (by HPLC)	≥95.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.