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Pyruvic-2 3-13C2 Acid Sodium Salt CAS NO 89196-78-1


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CAS No.:89196-78-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Pyruvic-2 3-13C2 Acid Sodium Salt is a stable, isotopically labeled sodium salt of pyruvic acid, specifically enriched with carbon-13 at the 2 and 3 positions. This high-purity labeled compound is essential for advanced metabolic research and analytical applications where precise isotopic tracing is required. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications such as metabolic flux analysis, NMR spectroscopy, and the synthesis of labeled active pharmaceutical ingredients (APIs).

Application

  • Metabolic Flux Analysis (MFA): A critical tracer for studying central carbon metabolism pathways in cells, tissues, or microorganisms.
  • NMR Spectroscopy & Mass Spectrometry: Serves as an internal standard or labeled precursor for quantitative analysis and structural elucidation in complex biological matrices.
  • Biochemical Research: Used in enzymatic studies and as a substrate to investigate the activity of enzymes like lactate dehydrogenase or pyruvate kinase.
  • Pharmaceutical Development: Employed in the synthesis of carbon-13 labeled drug candidates for pharmacokinetic and metabolic studies.
  • Diagnostic Agent Synthesis: Acts as a building block for producing labeled compounds used in advanced medical imaging and diagnostic tests.
  • Nutritional & Isotope Tracer Studies: Utilized in clinical and nutritional research to trace metabolic pathways in vivo.

Basic Information

Product Name Pyruvic-2 3-13C2 Acid Sodium Salt
CAS No. 89196-78-1
Molecular Formula C132H3NaO3
Molecular Weight 112.03 g/mol (for 13C2 labeled form)
Synonyms Sodium Pyruvate-2,3-13C2; 2-Oxopropanoic-2,3-13C2 Acid Sodium Salt; Pyruvic Acid-2,3-13C2 Sodium Salt; [2,3-13C2]Sodium Pyruvate; Sodium 2-oxopropanoate-2,3-13C2; 13C Labeled Sodium Pyruvate; Sodium α-ketopropionate-2,3-13C2; Pyruvate-2,3-13C2 Na Salt
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Quality Control

Our Pyruvic-2 3-13C2 Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and LC-MS, to confirm isotopic enrichment, chemical purity, and identity. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and specific tests are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Isotopic Enrichment ≥ 99 atom % 13C
Chemical Purity (HPLC) ≥ 98.0%
pH (5% solution) 6.0 - 8.0
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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