Description

2-Ethyl-5-Nitrophenylsulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the sulfonyl chloride group acts as a highly reactive electrophile for sulfonamide formation, and the nitro group provides a versatile handle for further chemical transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides with sulfonylurea or sulfonamide moieties.
• Dyestuff and Pigment Manufacturing: Used in the production of specialized azo dyes and colorants where the ethyl and nitro substituents modify hue and fastness properties.
• Polymer Chemistry: Monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical resistance.
• Chemical Research & Development: Versatile reagent for constructing complex molecular architectures in medicinal chemistry and material science projects.
• Ligand and Catalyst Preparation: Intermediate for synthesizing specialized ligands used in catalytic systems or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Ethyl-5-Nitrophenylsulfonyl Chloride
CAS No.	89189-34-4
Molecular Formula	C8H8ClNO4S
Molecular Weight	249.67 g/mol
Synonyms	1-(Chlorosulfonyl)-2-ethyl-5-nitrobenzene; 2-Ethyl-5-nitrobenzenesulfonyl chloride; 5-Nitro-2-ethylbenzenesulfonyl chloride; 2-Ethyl-5-nitrobenzene-1-sulfonyl chloride; (2-Ethyl-5-nitrophenyl)sulfonyl chloride; NSC 405131; Benzenesulfonyl chloride, 2-ethyl-5-nitro-
EINECS	Contact for details

Quality Control

Our 2-Ethyl-5-Nitrophenylsulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Keep away from strong bases, amines, alcohols, and moisture to prevent decomposition.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.