Description

Dabsyl-L-Proline is a high-purity, chromogenic derivative of the amino acid L-proline, specifically designed for advanced analytical applications. Its core value lies in its role as a critical reagent for the pre-column derivatization of amino acids, enabling highly sensitive detection and quantification via HPLC and LC-MS. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and food science industries who require precise amino acid analysis for process development, purity verification, and metabolic studies.

Application

• Amino Acid Analysis: Primary use as a derivatizing agent for the sensitive HPLC and UHPLC analysis of amino acids, including proline and hydroxyproline.
• Pharmaceutical QC: Used in the quality control of peptide-based drugs, biologics, and infusion solutions to quantify amino acid content and confirm composition.
• Biochemical Research: Essential tool in proteomics and metabolomics research for profiling amino acids in cell cultures, tissues, and biological fluids.
• Food & Nutrition Science: Applied in the analysis of protein hydrolysates, nutritional supplements, and food products to assess amino acid nutritional value.
• Diagnostic Reagent Manufacturing: Serves as a key component in the production of diagnostic kits and standards for clinical amino acid analysis.
• Method Development & Validation: Used as a reference standard in the development and validation of new analytical methods for amino acid detection.

Basic Information

Product Name	Dabsyl-L-Proline
CAS No.	89131-09-9
Molecular Formula	C₁₈H₂₃N₃O₄S
Molecular Weight	377.46 g/mol
Synonyms	4-Dimethylaminoazobenzene-4'-sulfonyl-L-proline; DABSYL-L-Proline; Dabsyl-Pro-OH; L-Proline, 1-[(4-dimethylamino)phenyl]azo]phenyl]sulfonyl]-; 1-(4-Dimethylaminoazobenzene-4'-sulfonyl)-L-proline; DABSYL-Proline; Dabsyl Proline Derivative; DABS Chloride Proline Adduct
EINECS	Contact for details

Quality Control

Our Dabsyl-L-Proline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for analytical applications. Each lot is tested using advanced chromatographic techniques, including HPLC and LC-MS, to confirm identity, potency, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.