Description

5-Chloronaphthalene-2-Sulfonyl Chloride is a versatile and reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a chlorosulfonyl group and a chloro-substituted naphthalene ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the naphthalene scaffold for bioactivity.
• Dyestuff and Pigment Manufacturing: Serves as a building block for creating high-performance, color-fast naphthalene-based dyes and organic pigments.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers, such as polyelectrolytes and engineering plastics.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other advanced functional materials.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules (proteins, nucleic acids) due to its reactive sulfonyl chloride group.

Basic Information

Product Name	5-Chloronaphthalene-2-Sulfonyl Chloride
CAS No.	89108-45-2
Molecular Formula	C10H6Cl2O2S
Molecular Weight	277.12 g/mol
Synonyms	2-Chlorosulfonyl-5-chloronaphthalene; 5-Chloro-2-naphthalenesulfonyl chloride; 5-Chloronaphthalene-2-sulfochloride; 2,5-Dichloronaphthalenesulfonyl chloride; NSC 403119; 1-Chloro-6-(chlorosulfonyl)naphthalene; 5-Chloronaphthalenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 5-Chloronaphthalene-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases, amines, alcohols, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.