Description

5,8,11,14-Eicosatetraenamide, n-Hydroxy-, (All-Z)- is a specialized hydroxamic acid derivative of arachidonic acid, a key polyunsaturated fatty acid. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential modulator of lipoxygenase and cyclooxygenase enzyme pathways. It serves as a critical intermediate and reference standard for researchers in medicinal chemistry, pharmacology, and lipidomics. The product is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly for investigating the activity and inhibition of lipoxygenase (LOX) enzymes.
• Medicinal Chemistry: Serves as a key synthetic intermediate or pharmacophore in the development of novel anti-inflammatory and pro-resolving lipid mediators.
• Pharmaceutical Development: Employed in preclinical research for studying metabolic pathways of eicosanoids and developing targeted therapies for inflammatory conditions.
• Lipidomics & Analytical Standards: Utilized as a high-purity calibration standard in mass spectrometry (LC-MS/GC-MS) for the qualitative and quantitative analysis of complex lipid samples.
• Cell Signaling Studies: Applied in cellular assays to probe the role of hydroxyeicosatetraenoic acid (HETE) derivatives in signal transduction and cellular response mechanisms.

Basic Information

Item	Detail
Product Name	5,8,11,14-Eicosatetraenamide, n-Hydroxy-, (All-Z)-
CAS No.	89016-98-8
Molecular Formula	C₂₀H₃₁NO₂
Molecular Weight	317.47 g/mol
Synonyms	N-Hydroxyarachidonamide; Arachidonohydroxamic Acid; 5Z,8Z,11Z,14Z-Eicosatetraenohydroxamic Acid; 20:4(n-6) Hydroxamic Acid; AAHA; Arachidonic Acid Hydroxamate; N-Hydroxyeicosa-5,8,11,14-tetraenamide
EINECS	Contact for details

Quality Control

Every batch of 5,8,11,14-Eicosatetraenamide, n-Hydroxy-, (All-Z)- is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.