Description

15-Fluoro-15-Deoxyprostaglandin E2 is a fluorinated analog of the primary prostaglandin E2, designed for enhanced metabolic stability and targeted biological activity. This compound is a critical research tool and synthetic intermediate for developing novel therapeutics and studying prostaglandin receptor pharmacology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on inflammation, oncology, and metabolic disease pathways.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel prostaglandin-based drug candidates targeting FP and EP receptors.
• Biochemical Research: Used as a stable probe to study the structure-activity relationships (SAR) of prostaglandins and their role in cellular signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Employed in the design and synthesis of fluorinated bioactive molecules to improve drug-like properties such as metabolic stability and membrane permeability.

Basic Information

Product Name	15-Fluoro-15-Deoxyprostaglandin E2
CAS No.	88736-32-7
Molecular Formula	C₂₀H₃₁FO₅
Molecular Weight	370.46 g/mol
Synonyms	15-Fluoro-15-deoxy-PGE2; 15-Fluoro-15-deoxyprostaglandin E2; PGE2, 15-fluoro-15-deoxy-; 5-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxy-5-fluoro-1-octen-1-yl]-5-oxocyclopentyl]pentanoic Acid; 15-Fluoro-15-deoxy-dinoprostone; Fluprostenol related compound; Prostaglandin E2 15-fluoro-15-deoxy analog
EINECS	Contact for details

Quality Control

Our 15-Fluoro-15-Deoxyprostaglandin E2 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; allow it to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.