Description

(2,4-Dichlorophenyl)-Methanesulfonyl Chloride CAS NO 88691-50-3 is a versatile and highly reactive organosulfur compound, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality as both an electrophile and a sulfonylating agent, enabling the efficient construction of complex molecular architectures. This intermediate is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern herbicides and fungicides, leveraging the dichlorophenyl moiety for enhanced bioactivity.
• Material Science Research: Acts as a precursor for functional polymers and advanced materials with specific sulfonyl group properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and covalent inhibitors for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects requiring specific sulfonyl chloride chemistry.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the sulfonyl chloride group facilitates coupling reactions.

Basic Information

Product Name	(2,4-Dichlorophenyl)-Methanesulfonyl Chloride
CAS No.	88691-50-3
Molecular Formula	C7H5Cl3O2S
Molecular Weight	259.54 g/mol
Synonyms	2,4-Dichlorophenylmethanesulfonyl Chloride; 1-(Chlorosulfonylmethyl)-2,4-dichlorobenzene; Methanesulfonyl chloride, (2,4-dichlorophenyl)-; (2,4-Dichlorobenzyl)sulfonyl chloride; NSC 405124; 88691-50-3; α,2,4-Trichlorotoluene-α-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our (2,4-Dichlorophenyl)-Methanesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.