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Argipressin, (β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid)(1)-Ile(2)-Ala(4)- CAS NO 88686-55-9


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CAS No.:88686-55-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Argipressin, (β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid)(1)-Ile(2)-Ala(4)- is a synthetic analog of the neurohypophysial hormone vasopressin, engineered for enhanced stability and targeted pharmacological activity. This high-purity peptide is critical for research and development in advanced therapeutic applications due to its specific receptor binding profile. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focusing on endocrinology, cardiovascular research, and novel drug delivery systems.

Application

  • Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
  • Biomedical Research: Used in preclinical studies to investigate vasopressin receptor (V1a, V2) mechanisms, signal transduction, and physiological responses.
  • Drug Discovery & Development: A key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics for conditions like diabetes insipidus, septic shock, or bleeding disorders.
  • Biochemical Assays: Employed in receptor binding assays, enzyme-linked immunosorbent assays (ELISA), and other in vitro diagnostic tests.
  • Peptide Chemistry Studies: Used as a model compound for studying structure-activity relationships (SAR) and peptide stability.

Basic Information

Product Name Argipressin, (β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid)(1)-Ile(2)-Ala(4)-
CAS No. 88686-55-9
Molecular Formula C46H65N13O12S2
Molecular Weight 1032.2 g/mol
Synonyms [1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid), 2-D-isoleucine, 4-alanine]arginine vasopressin; [1-(Mpa1), D-Ile2, Ala4]AVP; Desmopressin analog; d(CH2)5[D-Ile2,Ala4]AVP; Vasopressin V1a receptor antagonist analog; 1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid)-2-D-isoleucine-4-alanine-8-arginine vasopressin; Mpa1,D-Ile2,Ala4-Arg8-vasopressin
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Quality Control

Our Argipressin analog is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 97.0%
Single Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Acetate Content (HPIC) ≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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