Description

2-Methyl-3-Glutathionyl-1,4-Naphthoquinone is a specialized biochemical conjugate that plays a significant role in cellular redox biochemistry and detoxification pathways. This compound is valued for its unique structure, combining a naphthoquinone moiety with the tripeptide glutathione, making it a critical intermediate in the study of oxidative stress and metabolic processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors for applications in drug discovery, biochemical research, and as a reference standard.

Application

• Biochemical Research: Used as a key intermediate or reference standard in studies of quinone metabolism, glutathione conjugation (S-glutathionylation), and redox cycling.
• Pharmaceutical Development: Serves as a precursor or model compound in the research and development of novel therapeutics targeting oxidative stress-related diseases.
• Enzymology Studies: Employed as a substrate or inhibitor in assays to study the activity of enzymes like glutathione S-transferases (GSTs) and quinone reductases.
• Toxicology & Metabolite Identification: Acts as a characterized metabolite in toxicological studies for drugs or compounds that form reactive quinone species.
• Analytical Reference Standard: Provides a high-purity standard for HPLC, LC-MS, or NMR analysis in quality control and method development laboratories.
• Nutraceutical & Cosmetic Research: Investigated for its potential antioxidant properties and mechanisms in advanced cosmetic and nutraceutical formulations.

Basic Information

Product Name	2-Methyl-3-Glutathionyl-1,4-Naphthoquinone
CAS No.	88467-65-6
Molecular Formula	C20H23N3O9S
Molecular Weight	481.48 g/mol
Synonyms	2-Methyl-3-glutathionyl-1,4-naphthoquinone; 3-(Glutathion-S-yl)-2-methyl-1,4-naphthoquinone; Glutathionylmenadione; Menadione-glutathione conjugate; 2-Methyl-1,4-naphthoquinone-3-glutathione conjugate; 2-Methyl-3-S-glutathionyl-1,4-naphthalenedione; MNQ-SG; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-Glutathionyl-1,4-Naphthoquinone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature in a desiccator before opening to minimize moisture uptake and thermal stress.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.