Description

Arphamenine B is a potent and selective aminopeptidase inhibitor, a compound of significant interest in biochemical and pharmacological research. Its primary value lies in its ability to selectively inhibit specific metallo-aminopeptidases, making it a crucial tool for studying enzyme function, protein metabolism, and intracellular signaling pathways. This product is essential for researchers and developers in the fields of pharmaceutical discovery, proteomics, and academic biochemistry who require high-purity, reliable biochemical reagents.

Application

• Biochemical Research: Used as a specific inhibitor to study the physiological roles and mechanisms of aminopeptidases in cellular processes.
• Drug Discovery & Development: Serves as a lead compound or pharmacological tool for investigating novel therapeutic targets related to aminopeptidase activity in diseases.
• Proteomics & Enzyme Assays: Employed in in vitro enzymatic assays to characterize enzyme kinetics, screen for other inhibitors, or validate assay systems.
• Academic & Institutional Laboratories: A key reagent for fundamental research into protein degradation, antigen presentation, and neuropeptide regulation.
• Cell Biology Studies: Applied to modulate intracellular peptide processing to understand its impact on cell function, proliferation, and apoptosis.

Basic Information

Product Name	Arphamenine B
CAS No.	88465-81-0
Molecular Formula	C₁₅H₂₀N₄O₃
Molecular Weight	304.35 g/mol
Synonyms	Arphamenine B; N-[(2S)-2-Amino-5-(diaminomethylideneamino)pentanoyl]-L-leucyl-L-phenylalaninal; Bestatin derivative; Aminopeptidase Inhibitor Arphamenine B; (S)-2-Amino-5-(diaminomethylideneamino)-N-[(2S)-1-[[(2S)-1-oxo-3-phenyl-1-[(phenylmethyl)amino]propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pentanamide
EINECS	Contact for details

Quality Control

Our Arphamenine B is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.