Description

Sarcochenodeoxycholic Acid is a secondary bile acid derivative with significant biochemical and pharmacological relevance. This compound serves as a critical intermediate and reference standard in the research and development of therapeutic agents targeting liver and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents. Its precise structure and purity make it essential for studies involving bile acid metabolism, receptor interaction, and cholestatic disease models.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of novel therapeutic bile acids and hepatoprotective agents.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, transport, and signaling pathways.
• Cell Culture & In Vitro Studies: Employed in cell-based assays to investigate the effects of bile acids on hepatocytes, cholangiocytes, and intestinal cells.
• Analytical Standard: Serves as a high-purity calibration standard for analytical methods such as HPLC, LC-MS, and GC-MS in quality control and metabolomics.
• Metabolic Disease Research: Applied in preclinical research models for diseases like cholestasis, non-alcoholic fatty liver disease (NAFLD), and gallstone formation.
• Enzymology Studies: Used as a substrate or inhibitor to study the activity of enzymes involved in bile acid synthesis and conjugation.

Basic Information

Product Name	Sarcochenodeoxycholic Acid
CAS No.	88446-86-0
Molecular Formula	C₂₄H₄₀O₄
Molecular Weight	392.57 g/mol
Synonyms	3α,7α-Dihydroxy-5β-cholan-24-oic Acid; Sarco-CDCA; N-Methylchenodeoxycholic Acid Amide; 7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid (related oxo-form); Chenodeoxycholic Acid Derivative; Bile Acid Intermediate; 5β-Cholan-24-oic Acid-3α,7α-diol; NSC 113233
EINECS	Contact for details

Quality Control

Our Sarcochenodeoxycholic Acid is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every shipment. We can support development projects requiring compliance with ICH guidelines or other specific regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider holding under inert atmosphere to minimize oxidation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.