Description

o-Desmethylbouvardin is a key chemical intermediate and reference standard of significant interest in pharmaceutical research and development. Its value lies in its role as a structural analog and potential metabolite of bouvardin, a cyclopeptide with documented biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, analytical method development, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of bouvardin and related compounds in research and quality control laboratories.
• Chemical Intermediate: Serves as a critical building block in the synthetic pathways for novel cyclopeptides and complex natural product analogs.
• Metabolite Studies: Employed in pharmacokinetic and drug metabolism research to understand the biotransformation pathways of bouvardin.
• Biological Activity Screening: Used as a test compound in bioassays to investigate structure-activity relationships (SAR) and identify new pharmacological targets.
• Analytical Method Development: Essential for developing and validating chromatographic methods (e.g., HPLC, LC-MS) for the detection and quantification of related substances.

Basic Information

Product Name	o-Desmethylbouvardin
CAS No.	88360-88-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Desmethylbouvardin; Bouvardin, desmethyl-; Bouvardin metabolite; 6-O-Desmethylbouvardin; NSC 339656; Cyclo[(2S,5R,8S,11S,14S,17S)-5-benzyl-14-[(2S)-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)ethyl]-11-(4-hydroxybenzyl)-2,8,17-trimethyl-3,6,9,12,15,18-hexaoxo-1-oxa-4,7,10,13,16-pentaazacyclooctadecan-17-yl]acetic acid (IUPAC); Bouvardin analog
EINECS	Contact for details

Quality Control

Our o-Desmethylbouvardin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is characterized using advanced analytical techniques, including NMR and mass spectrometry, for definitive structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.