Description

(4R,5Z,7E,12S,14Z)-4,12,20-Tris(Acetyloxy)-9-Oxo-5,7,10,14-Prostatetren-1-Oic Acid Methyl Ester CAS NO 88216-91-5 is a high-purity, synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. Its complex stereochemistry makes it a critical building block for synthesizing bioactive molecules targeting specific physiological pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel therapeutics in areas such as inflammation, immunology, and reproductive health.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and a tool compound in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
• Drug Discovery: Serves as a key scaffold for medicinal chemistry programs aimed at developing new anti-inflammatory or cytoprotective agents.
• Process Development: Employed in scaling up and optimizing synthetic routes for complex prostaglandin derivatives under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis, chemical biology, and physiology.

Basic Information

Product Name	(4R,5Z,7E,12S,14Z)-4,12,20-Tris(Acetyloxy)-9-Oxo-5,7,10,14-Prostatetren-1-Oic Acid Methyl Ester
CAS No.	88216-91-5
Molecular Formula	C27H38O8
Molecular Weight	490.59 g/mol
Synonyms	Methyl (4R,5Z,7E,12S,14Z)-4,12,20-Triacetoxy-9-oxoprosta-5,7,10,14-tetraenoate; 9-Oxo-4,12,20-Triacetoxy-5,7,10,14-prostatetrenoic Acid Methyl Ester; Prostaglandin A2 Methyl Ester Triacetate; PGA2 Methyl Ester Triacetate; 4,12,20-Tri-O-acetyl-9-oxo-PGA2 Methyl Ester; (4R,5Z,7E,12S,14Z)-4,12,20-Triacetoxy-9-oxoprosta-5,7,10,14-tetraenoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (4R,5Z,7E,12S,14Z)-4,12,20-Tris(Acetyloxy)-9-Oxo-5,7,10,14-Prostatetren-1-Oic Acid Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management principles, and material can be supplied to meet specific customer requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.