Description

Dibenzo(A,L)Pyrene 11,12-Dihydrodiol is a high-purity, polycyclic aromatic hydrocarbon (PAH) metabolite of significant research interest. This compound is crucial for toxicological and environmental studies, serving as a key reference standard and metabolic intermediate. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in carcinogenicity studies, metabolic pathway analysis, and environmental contaminant monitoring.

Application

• Biochemical Research: Used as a critical metabolite in studies investigating the metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs) and their role in carcinogenesis.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for the calibration of analytical instruments like HPLC, GC-MS, and LC-MS in environmental and biological sample analysis.
• Toxicology Studies: Essential for in vitro and in vivo assays to assess the genotoxicity, mutagenicity, and DNA adduct formation potential of PAH derivatives.
• Environmental Monitoring: Employed in method development and validation for detecting and quantifying PAH metabolites in air, water, soil, and biological tissues.
• Pharmaceutical Development: Used in early-stage research to understand drug metabolism interactions and the bioactivation of complex organic molecules.

Basic Information

Product Name	Dibenzo(A,L)Pyrene 11,12-Dihydrodiol
CAS No.	88191-01-9
Molecular Formula	C24H16O2
Molecular Weight	336.38 g/mol
Synonyms	11,12-Dihydroxy-11,12-dihydrodibenzo[a,l]pyrene; Dibenzo[a,l]pyrene-11,12-dihydrodiol; DB[a,l]P-11,12-dihydrodiol; 11,12-Dihydrodiol of Dibenzo(a,l)pyrene; Dibenzo(a,l)pyrene 11,12-diol; PAH Metabolite Standard; DBALP-11,12-dihydrodiol
EINECS	Contact for details

Quality Control

Our Dibenzo(A,L)Pyrene 11,12-Dihydrodiol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.