Description

1H-Indene-5-Sulfonyl Chloride, 2,3-Dihydro-6-Methoxy- is a specialized sulfonyl chloride derivative of indene, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its reactivity as an electrophilic sulfonylation agent, enabling the efficient introduction of the sulfonyl group to construct complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups for enhanced activity.
• Material Science Research: Employed in the creation of novel polymers or organic electronic materials where the indene-sulfonyl moiety can impart specific electronic or physical properties.
• Chemical Biology Probes: Acts as a reagent for modifying proteins or other biomolecules to study biological pathways or develop diagnostic tools.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Indene-5-Sulfonyl Chloride, 2,3-Dihydro-6-Methoxy-
CAS No.	88040-92-0
Molecular Formula	C10H9ClO3S
Molecular Weight	244.69 g/mol
Synonyms	6-Methoxy-2,3-dihydro-1H-indene-5-sulfonyl chloride; 5-(Chlorosulfonyl)-6-methoxy-2,3-dihydro-1H-indene; 6-Methoxyindan-5-sulfonyl chloride; 88040-92-0; 6-Methoxy-2,3-dihydroindene-5-sulfonyl chloride; 5-Methoxy-6-sulfonylchloride indane
EINECS	Contact for details

Quality Control

Our production of 1H-Indene-5-Sulfonyl Chloride, 2,3-Dihydro-6-Methoxy- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. While typically supplied as a high-purity research chemical, specifications can be aligned with customer requirements for advanced synthetic work. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.