Description

Fostriecin Sodium Salt CAS NO 87860-39-7 is a potent and selective inhibitor of protein phosphatase 2A (PP2A) and protein phosphatase 4 (PP4). This compound is a critical research tool for studying cell signaling pathways, particularly those involving serine/threonine phosphatases in cell cycle regulation and DNA damage response. It is primarily utilized by researchers and scientists in the fields of oncology, molecular biology, and biochemistry for in vitro studies and target validation.

Application

• Biochemical Research: A key tool compound for investigating the role of PP2A and PP4 in cellular signaling cascades, apoptosis, and cell cycle progression.
• Oncology Research: Used in studies to understand tumor suppression mechanisms and to explore potential therapeutic targets in cancer pathways.
• Molecular Biology: Employed in vitro to modulate phosphatase activity, aiding in the study of protein phosphorylation/dephosphorylation events.
• Drug Discovery: Serves as a reference standard and a pharmacological probe in high-throughput screening and target validation assays.
• Academic Research: Essential for university and institutional labs focused on signal transduction and post-translational modifications.

Basic Information

Product Name	Fostriecin Sodium Salt
CAS No.	87860-39-7
Molecular Formula	C₂₄H₃₄NaO₁₁P
Molecular Weight	552.48 g/mol
Synonyms	Fostriecin sodium; CI-920 sodium salt; PD 110,161; NSC 339638; (1R,2S,5S,6R,9S,10S,11R,12S,13S,14R,15R,16S,17S,18R)-5,6,11,12,13,14,15,16,17,18-Decahydro-14-hydroxy-5,9:12,16-diepoxy-6,10:17,18-dimetheno-1H-2,8a-methanocycloocta[cd]pentalen-1-yl Dihydrogen Phosphate Sodium Salt
EINECS	Contact for details

Quality Control

Our Fostriecin Sodium Salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.