Description

Bryostatin 2 is a potent, naturally occurring macrocyclic lactone isolated from marine bryozoans. This compound is of significant interest for its unique biological activity as a protein kinase C (PKC) modulator, which underpins its value in advanced biomedical research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies investigating novel therapeutic pathways in oncology, neurology, and immunology.

Application

• Biomedical Research: A critical tool for studying protein kinase C (PKC) signaling pathways, cellular differentiation, and apoptosis.
• Oncology Research: Investigated for its potential to induce apoptosis in cancer cells and as a candidate for combination therapies.
• Neurological Disorder Studies: Explored for neuroprotective and cognitive-enhancing effects in models of Alzheimer's disease and memory disorders.
• Immunology Research: Used to study immune cell activation and modulation for potential applications in vaccine adjuvants or autoimmune diseases.
• Drug Discovery & Development: Serves as a lead compound or a pharmacological probe in high-throughput screening and mechanism-of-action studies.
• Academic & Clinical Research: Employed in university and institutional labs for fundamental research into cell biology and translational medicine.

Basic Information

Item	Details
Product Name	Bryostatin 2
CAS No.	87745-28-6
Molecular Formula	C47H70O17
Molecular Weight	907.05 g/mol
Synonyms	Bryostatin II; Bryostatin-2; NSC 339555; (1S,3S,4S,5R,9R,11S,12R,13S,14S,16S,19R,21S,23S,25S,27S,29S,31S,33R,35S)-33-[(2S,3S,4R)-3,4-Dihydroxy-2-methyloxan-4-yl]-5,9,11,14,19,21,23,27,29,31,35-undecahydroxy-3,12,16,25-tetramethyl-2,36-dioxa-15,34-diazanonacyclo[28.6.1.11,35.13,27.14,23.15,20.07,18.09,17.024,32]hexatriaconta-7(18),8,10,13,15,20,22,24(32),26,30-decaen-6-one
EINECS	Contact for details

Quality Control

Every batch of Bryostatin 2 is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Comprehensive testing includes HPLC for purity determination, spectroscopic identification (NMR, MS), and residual solvent analysis. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.