Description

2-(Isoxazol-5-Yl)Benzene-1-Sulfonyl Chloride (Wxc09362) is a high-purity sulfonyl chloride derivative, a key synthetic intermediate in modern organic chemistry. Its value lies in its highly reactive sulfonyl chloride group, which enables efficient sulfonamide bond formation under mild conditions, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that leverage the sulfonamide pharmacophore for enhanced bioactivity.
• Material Science Research: Serves as a precursor for creating functional polymers and advanced materials with tailored surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Isoxazol-5-Yl)Benzene-1-Sulfonyl Chloride (Wxc09362)
CAS No.	87488-64-0
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	5-(2-Chlorosulfonylphenyl)isoxazole; 1-Chlorosulfonyl-2-(5-isoxazolyl)benzene; 2-(1,2-Oxazol-5-yl)benzenesulfonyl chloride; 2-(Isoxazol-5-yl)benzenesulfonyl chloride; WXC09362; Benzenesulfonyl chloride, 2-(5-isoxazolyl)-; 2-(5-Isoxazolyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Isoxazol-5-Yl)Benzene-1-Sulfonyl Chloride is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.