Description

Naxaprostene is a synthetic prostaglandin analog with specific biological activity. This compound is valued for its role as a key intermediate in advanced pharmaceutical synthesis, particularly in the development of therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the production of specialized medications. The material is supplied to meet the stringent purity and consistency requirements of these critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or tool compound in pharmacological and biological studies investigating prostaglandin pathways.
• Ophthalmic Drug Development: Potential intermediate for the research and production of medications targeting intraocular pressure.
• Veterinary Medicine: May be employed in the development of treatments for animal health applications.

Basic Information

Product Name	Naxaprostene
CAS No.	87269-59-8
Molecular Formula	C₂₃H₃₈O₅
Molecular Weight	394.55 g/mol
Synonyms	9-Deoxo-9a-homo-9a-nitrilo-PGF1α; 9a-Aza-11,15-dihydroxy-15-methyl-9-oxoprosta-5,13-dien-1-oic Acid; 15-Methyl-9-oxo-9a-aza-11,15-dihydroxyprosta-5,13-dien-1-oic Acid; 9a-Aza-11,15-dihydroxy-15-methyl-9-oxoprosta-5,13-dienoic Acid; Naxaprostene (free acid)
EINECS	Contact for details

Quality Control

Our Naxaprostene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP guidelines for pharmaceutical intermediates, and specifications can be aligned with client-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.