Description

3-(2'-Deoxyribofuranosyl)Pyrimido(1,2-A)Purin-10(3H)-One is a specialized nucleoside analogue of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard in the study of nucleic acid chemistry, DNA damage, and related biological pathways. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in the development of novel therapeutics and analytical methods.

Application

• Biochemical Research: Used as a key intermediate or reference standard in studies of DNA adducts, oxidative stress, and nucleoside metabolism.
• Pharmaceutical Development: Serves as a precursor or analytical standard in the R&D of potential chemotherapeutic agents and nucleotide-based drugs.
• Diagnostic Reagents: Employed in the formulation of high-sensitivity diagnostic assays and kits for detecting specific biomarkers or DNA lesions.
• Academic Research: A vital tool in university and institutional labs for fundamental research in molecular biology, genetics, and toxicology.
• Contract Research Organizations (CROs): Used as a certified reference material (CRM) for method validation and quality control in analytical services.

Basic Information

Product Name	3-(2'-Deoxyribofuranosyl)Pyrimido(1,2-A)Purin-10(3H)-One
CAS No.	87171-83-3
Molecular Formula	C₁₅H₁₅N₅O₄
Molecular Weight	329.31 g/mol
Synonyms	M1dG; Malondialdehyde-2'-deoxyguanosine Adduct; Pyrimidopurinone Adduct of dG; 3-(2'-Deoxy-β-D-erythro-pentofuranosyl)pyrimido[1,2-a]purin-10(3H)-one; 1,N²-Propanodeoxyguanosine; M1G-dR; M1dG Adduct
EINECS	Contact for details

Quality Control

Our production of 3-(2'-Deoxyribofuranosyl)Pyrimido(1,2-A)Purin-10(3H)-One adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and structural confirmation via NMR and MS. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.