Description

4'-(2-Ethyldiazomalonyl)Digitoxigenin Monodigitoxiside is a specialized, high-purity chemical intermediate derived from the digitoxigenin core structure, modified with a reactive diazomalonyl group. This compound is of significant value for the synthesis of novel cardiac glycoside derivatives and for use as a key building block in advanced pharmaceutical research and development. It is primarily needed by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors who are engaged in drug discovery, medicinal chemistry, and the development of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel cardiac glycosides and other steroidal drugs with potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and the development of targeted molecular probes.
• Biochemical Tool Compound: Used in biochemical assays to study the mechanisms of Na+/K+-ATPase inhibition and related cardiac pathways.
• Labeled Compound Synthesis: The reactive diazo group makes it suitable for photoaffinity labeling studies and the preparation of tagged derivatives for tracking and imaging.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value steroidal molecules.
• Academic & Institutional Research: Utilized in university and research institute laboratories for fundamental studies in organic chemistry and pharmacology.

Basic Information

Product Name	4'-(2-Ethyldiazomalonyl)Digitoxigenin Monodigitoxiside
CAS No.	87168-26-1
Molecular Formula	C₃₃H₄₆O₁₀N₂
Molecular Weight	630.73 g/mol
Synonyms	Digitoxigenin 3-O-[4'-(2-ethyldiazomalonyl)]-β-D-digitoxoside; 3β-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide 4'-(2-ethyldiazomalonate); 4'-(2-Ethyldiazomalonyl)digitoxigenin digitoxoside; Ethyldiazomalonyl-digitoxigenin-monodigitoxoside; Cardiac glycoside diazo intermediate; CAS 87168-26-1
EINECS	Contact for details

Quality Control

Our 4'-(2-Ethyldiazomalonyl)Digitoxigenin Monodigitoxiside is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability, consistency, and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.