Description

Prolyl Endopeptidase Inhibitor Ii is a potent and selective synthetic inhibitor of the serine protease prolyl endopeptidase (PEP). This compound is critical for biochemical research and pharmaceutical development, enabling precise modulation of enzymatic activity. It is primarily utilized by researchers in neuroscience, endocrinology, and drug discovery for studying neuropeptide metabolism and related disease pathways.

Application

• Biochemical Research: A key tool for studying the function and regulation of prolyl endopeptidase (PEP) in vitro and in cellular assays.
• Neuroscience Studies: Used to investigate the role of PEP in the metabolism of neuropeptides (e.g., vasopressin, substance P) and its implications for memory and learning processes.
• Drug Discovery & Development: Serves as a reference compound and lead structure for developing novel therapeutics targeting PEP for conditions like Alzheimer's disease, depression, and other cognitive disorders.
• Enzymology: Employed in kinetic studies and enzyme characterization to understand substrate specificity and inhibition mechanisms.
• Diagnostic Assay Development: Used as a control inhibitor in the development of high-throughput screening assays for PEP activity.

Basic Information

Product Name	Prolyl Endopeptidase Inhibitor Ii
CAS No.	86925-97-5
Molecular Formula	C20H28N4O4
Molecular Weight	388.47 g/mol
Synonyms	Z-Pro-Prolinal; Z-Pro-prolinal; Benzyloxycarbonyl-Pro-prolinal; Prolyl Endopeptidase Inhibitor II; PEP Inhibitor II; Z-Prolyl-prolinal; (S)-1-(((S)-1-((Benzyloxy)carbonyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxaldehyde); S 17092
EINECS	Contact for details

Quality Control

Our Prolyl Endopeptidase Inhibitor Ii is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.